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Core Facilities at UNC

by Rob Lineberger last modified 2006-03-20 12:22

These Core facilities at UNC and surrounding areas provide assistance with proteomics, microscopy, immunohistochemistry, transgenic technologies, and other biomedical arenas.

Animal Clinical Chemistry and Gene Expression can assist research investigators who would greatly benefit from availability of service that replicates for animals the laboratory tests that are routine for humans.

Animal Models Core Facility makes animal models of human disease for medical researchers by creating genetically modified mice.

Animal Studies Facility services provided range from tumor passage to production of acsites fluid for monoclonal antibody production.

Biosafety Facility consists of two containment rooms. One is maintained at a BSL2 containment level, while the other is maintained at a BSL3 level and used primarily for work with HIV.

Biostatistics provides expert consultation in biostatistics during all phases of research projects.

CCBC Microarray Facility Facility is available to researchers with the NHLBI Grant and those who are doing cardiovascular research. We provide RNA quality check and full hybridization services.

Clinical Nutrition Research Center works to combine basic nutrition and studies of populations in an effort to answer questions on how the food we eat affects our bodies.

DNA Sequencing Facility generates DNA sequence data on automated DNA sequencing machines from DNA templates and primers provided by the user.

Electron Microscopy Facility offers services in EM, photography and image processing.

Flow Cytometry Facility provides state-of-the-art analytic and sorting technologies and services to Cancer Center members.

Genomics Core and Microarray Facility produce human and mouse DNA oligo microarrays and provide traning and bioinformatic support for researchers.

Histopathology Facility offers high-quality processing of fixed tissues into hematoxylin and eosin-stained paraffin slides, as well as the preparation of frozen tissue sections.

Light Microscopy Facility provides microscopy services to UNC researchers and access to state-of-the-art microscopy, expert assistance in its utilization and interpretation, and consultation in immuno methods and image interpretation and measurement.

Michael Hooker Microscopy Facility provides advanced digital light microscopy and image processing resources, and is available to users from the UNC Chapel Hill campus on a fee for use basis.

Microprotein Sequencing and Peptide Synthesis Facility synthesizes amino acid sequences.

Nucleic Acids Core Facility provides investigators with low-cost, high-quality oligonucleotides for use in a wide range of applications including DNA sequencing, PCR, cDNA/RNA synthesis, hybridization, in vitro mutagenesis and anti-sense inhibition of gene expression.

Oligonucleotide Synthesis Core Facility produces and purifies oligonucleotides for use in genetic research experiments, such as PCR, DNA sequencing, primer extension, and as hybridization probes.

Physiology Imaging Confocal Facility the confocal microscope is available for use by members of the neuroscience and research communities at the University of North Carolina.

Proteomics Core Laboratory provides UNC with a state-of-the-art facility to identify proteins and to assist in the characterization of protein modification and differential expression.

Structural BioInformatics Core Facility services include Sequence Alignment, Secondary Structure Predictions, Domain Analysis.

Tissue Culture and Molecular Biology Support a full-service cell culture shared resource and provides a wide variety of services and products at substantial discounts.

Tissue Procurement Facility procures fresh and frozen tissue, both tumor and non-tumor from the operating rooms at UNC Hospitals.

Vector Core Facility maintains and distributes a library of recombinant adenovirus (rAd) and recombinant adeno-associated virus (rAAV) vectors, as well as retroviral vectors.

 

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