The CCBC offers many opportunities for research training in the cardiovascular sciences. The research programs of the investigators in our center cover all important aspects of cardiovascular pathophysiology, and trainees gain experiences in cutting edge scientific applications of molecular biology, genetics, genomics (including microarray analyses), developmental biology, animal models of disease, and biochemistry (including advanced mass spectroscopy applications). Interested individuals are always encouraged to inquire directly to investigators about potential opportunities. At the present time, the center supports trainees at the predoctoral, medical student, and post-doctoral levels.

The Integrative Vascular Biology Predoctoral Training Program is supported by funding from the National Institutes of Health and is directed by Nobuyo Maeda. Trainees are selected among graduate students from multiple departments and curricula across the Schools at UNC-Chapel Hill during the spring semester of their first or second year. The goal of the IVB program is to train students who will be capable of solving problems in vascular disease in the post-genomic era, implementing an integrative approach to studies of complex model systems through multidisciplinary collaborations. The IVB program seeks to unite students who are working or intend to work in the field of vascular biology and to provide an environment that encourages collaborations and research involving more than one laboratory.

Medical students at UNC have opportunities to participate in short-term and year-long research experiences as well as in dual degree programs such as the NIH-funded M.D./Ph.D. program. These opportunities are coordinated through the Office of Medical Student Research, which is directed by Cam Patterson, M.D.. The investigators in the CCBC are frequent mentors for students participating in these programs, which provide a unique opportunity for medical students to learn the methods and dogma of clinical cardiovascular science. Interested medical students from UNC and elsewhere are encouraged to contact us for more information. Post-doctoral Research Training in the CCBC The CCBC provides a wonderful opportunity for post-doctoral trainees interested in careers in cardiovascular science. The CCBC is a rich environment for training, with seminar series, joint lab meetings, and all of the scientific resources available through the CCBC and at UNC in general. Because the CCBC is growing rapidly, many investigators currently have post-doctoral positions available, and interested applicants are encouraged to contact investigators directly. Presently, the following investigators have available positions:

Cam Patterson, MD

POST-DOCTORAL FELLOW positions are available in the Patterson laboratory to study signaling and transcriptional events in the vascular endothelium and smooth muscle in the setting of developmental processes, angiogenesis, and atherosclerosis. Fellows will use biochemical, developmental, and molecular techniques and knockout mice generated in our laboratory. For examples of our work, please see Journal of Biological Chemistry. 276: 39197-39205 (2001), Journal of Clinical Investigation. 108: 1513-1522 (2001), Nature Cell Biology, 3: 93-96 (2001). Expertise in signaling, developmental methods, animal models, or histologic methods is beneficial.

For more information regarding these positions, please contact: Cam Patterson, M.D. Carolina Cardiovascular Biology Center University of North Carolina at Chapel Hill 5.109 Neurosciences Building 103 Mason Farm Road, CB#7126 Chapel Hill, NC 27599-7126 (919) 843-6477 e-mail: cpatters@med.unc.edu

Marschall Runge, MD/Ph.D.

POST-DOCTORAL FELLOW positions are available in the Runge laboratory to pursue innovative research on the role of reactive oxygen species on the progression of atherosclerosis. (see American Journal of Physiology 2001; 280(6):H2779-88 and Journal of Clinical Investigation. 2001; 108(10):1513-22).
Applicants should have experience in basic molecular and cell biology techniques; some projects will also employ mouse models of cardiovascular physiology. Salaries range from $29,000 - $36,000. UNC-CH is an Equal Opportunity/ADA Employer.

For more information regarding these positions, please contact: Marschall Runge, M.D., Ph.D. Carolina Cardiovascular Biology Center University of North Carolina at Chapel Hill 5109 Neurosciences Building 103 Mason Farm Road, CB#7126 Chapel Hill, NC 27599-7126 e-mail: nrmadama@med.unc.edu